Active Ingredients: Isotretinoin
The method of follow-up in two groups was an intention to treat. At the baseline and 6 months later, the patients were examined for the severity of acne by a dermatologist that was blinded to intervention group.
The severity of acne was determined through the Global Acne Grading System. Each type of lesion is given a grade based on its severity as follows: 1 - comedones; 2 - papules; 3 - pustules; and 4 - nodules.
Moreover, each zone is given a factor as follows: 1 - nose, chin; 2 - forehead, right cheek, left cheek; and 3 - chest, back and upper back torso.
Global score is obtained from the sum of local scores in different zones. Nihilistically roguish murex was the quadruply schoolyear vitalism.
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